{"id":89840,"date":"2019-10-02T08:29:39","date_gmt":"2019-10-02T06:29:39","guid":{"rendered":"https:\/\/likemetkovic.hr\/?p=89840"},"modified":"2019-10-02T08:30:07","modified_gmt":"2019-10-02T06:30:07","slug":"zbog-sumnje-da-sadrze-karcinogene-povuceni-ranital-i-ranix-a-peptoran-i-drugi-se-jos-ispituju","status":"publish","type":"post","link":"https:\/\/likemetkovic.hr\/portal\/zbog-sumnje-da-sadrze-karcinogene-povuceni-ranital-i-ranix-a-peptoran-i-drugi-se-jos-ispituju\/","title":{"rendered":"Zbog sumnje da sadr\u017ee karcinogene povu\u010deni Ranital i Ranix, a Peptoran i drugi se jo\u0161 ispituju"},"content":{"rendered":"

Radi se o lijekovima koji se nabavljaju bez recepta i koje na svoju ruku<\/em> koriste tisu\u0107e ljudi sa \u017eelu\u010danim problemima, prenosi Jutarnji list<\/a>.<\/strong><\/p>\n

Ameri\u010dka agencija za hranu (FDA) i Europska agencija za lijekove (EMA) zatra\u017eile su povla\u010denje s tr\u017ei\u0161ta lijekova protiv \u017egaravice koji sadr\u017ee djelatnu tvar ranitidin<\/strong> proizvo\u0111a\u010da Saraca Laboratories Ltd.<\/p>\n

Ranitidin sadr\u017ee iznimno popularni lijekovi koji se dobivaju bez recepta, poput Peptorana, Ranitala, Gastrobela, Ranixa ili Rantina<\/strong>, koje u Hrvatskoj svakodnevno koriste tisu\u0107e ljudi. Razlog povla\u010denja je to \u0161to su ispitivanja pokazala da neki od tih lijekova sadr\u017ee one\u010di\u0161\u0107enje pod nazivom N-nitrozodimetilamin (NDMA), koji se klasificira kao vjerojatni humani karcinogen, odnosno tvar koja bi mogla uzrokovati rak.<\/p>\n

– U Hrvatskoj su povu\u010dene filmom oblo\u017eene tablete Ranital od 150 mg, Ranital od 300 mg i Ranital S od 150 mg te filmom oblo\u017eene tablete Ranix od 150 mg i Ranix od 300 mg. No, dostupni su drugi odobreni lijekovi s djelatnom tvari ranitidin drugog proizvo\u0111a\u010da, koja trenuta\u010dno nije zahva\u0107ena sumnjom na navedenu neispravnost u kakvo\u0107i te se stoga ti lijekovi ne povla\u010de s tr\u017ei\u0161ta.<\/em><\/p>\n

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Rije\u010d je o Gastrobelu od 150 mg, \u010diji je nositelj odobrenja tvrtka Belupo lijekovi i kozmetika, te o Peptoranu od 150 mg, Peptoranu od 75 mg i Peptoranu Max od 150 mg, sve filmom oblo\u017eenim tabletama, \u010diji je nositelj odobrenja Pliva Hrvatska te Rantin 150 mg filmom oblo\u017eene tablete nositelja odobrenja Farmal<\/em> – rekla nam je Maja Ba\u0161i\u0107<\/strong>, glasnogovornica Hrvatske agencije za lijekove i medicinske proizvode (Halmed).<\/div>\n<\/div>\n<\/div>\n
Preventiva<\/strong><\/h5>\n

Kako saznajemo, tvrtka Sandos, koja proizvodi Ranital, iz hrvatskih je ljekarni, u suradnji s HALMED-om, preventivno povukla sve zalihe tog lijeka.<\/p>\n

Stru\u010dnjaci isti\u010du da se svi lijekovi na bazi ranitidina jo\u0161 istra\u017euju te bi se i drugi lijekovi mogli na\u0107i na zabranjenoj listi.<\/p>\n

– Sredi\u0161nje eti\u010dko povjerenstvo (SEP) uskoro \u0107e raspravljati o toj odluci EMA-e. Naime, za mnoge lijekove treba pri\u010dekati niz godina da bi se mo\u017eda utvrdilo da mogu biti i \u0161kodljivi za pacijente. Sigurno je da \u0107emo razmotriti sve dokaze i vidjeti kako \u0107emo postupiti u ovom slu\u010daju u Hrvatskoj<\/em> – ka\u017ee gastroenterolog prof. dr.\u00a0Nadan Rustemovi\u0107<\/strong>\u00a0iz KBC-a Zagreb. Dodaje da je problem \u0161to se ova vrsta lijekova prodaje i bez recepta, pa je te\u0161ko znati koliki je razmjer problema.<\/p>\n

No, on sasvim sigurno nije mali. Mnogi sa \u017eelu\u010danim problemima razmi\u0161ljaju: \u201cMu\u010di me \u017eelu\u010dana kiselina, pa su moje \u017egaravice postale vrlo \u010deste. No, rije\u0161im to tako da odem u ljekarnu, kupim neki od lijekova \u2018neutralizatora\u2019 i problema nema.\u201d<\/p>\n

Lijekove nabavljaju bez recepta, pa i bez konzultacije s lije\u010dnikom. Oni s djelatnom tvari ranitidin djeluju tako da blokiraju histaminske receptore u \u017eelucu i smanjuju stvaranje \u017eelu\u010dane kiseline. Koriste se za lije\u010denje i prevenciju stanja uzrokovanih vi\u0161kom kiseline u \u017eelucu, kao \u0161to su \u017egaravica i \u017eelu\u010dani ulkusi. Stru\u010dnjaci su sigurni da kod pacijenata koji su kratkotrajno koristili sporne lijekove ne\u0107e biti nikakvih posljedica.<\/p>\n

U SAD-u je dio tih lijekova ve\u0107 povu\u010den iz ljekarni, a isto se doga\u0111a i u zemljama EU. Istina, u svim uputama za kori\u0161tenje spornih lijekova navedeno je da se ne bi smjeli uzimati dulje od \u0161est dana bez konzultacije s lije\u010dnikom, ali te\u0161ko je vjerovati da se ve\u0107ina pacijenta pridr\u017eava te preporuke.<\/p>\n

Europska agencija za lijekove (EMA) jo\u0161 je prije dva tjedna zapo\u010dela ocjenu lijekova koji sadr\u017ee djelatnu tvar ranitidin nakon \u0161to su ispitivanja pokazala da neki od ovih lijekova sadr\u017ee one\u010di\u0161\u0107enje pod nazivom N-nitrozodimetilamin (NDMA). Naime, na temelju ispitivanja na \u017eivotinjama, NDMA se klasificira kao vjerojatni humani karcinogen, odnosno tvar koja bi mogla uzrokovati rak. NDMA je prisutan u odre\u0111enoj hrani i vodi, me\u0111utim, ne o\u010dekuje se da je \u0161tetan kada se unosi u vrlo malim koli\u010dinama.<\/p>\n

Potro\u0161nja svih lijekova za smanjenje \u017eelu\u010dane kiseline u samo jednoj godini pove\u0107ana je za 10 posto.<\/p>\n

– Smatram da se predaleko oti\u0161lo u prodaji lijekova bez recepta jer to zna\u010di i uzimanje lijekova bez nadzora lije\u010dnika. Dovoljno je spomenuti paracetamol, lijek za sni\u017eavanje temperature, koji se tako\u0111er kupuje bez recepta, a u slu\u010daju predoziranja mo\u017ee biti smrtonosan. Problem je svih OTC lijekova \u0161to se uzimaju nekriti\u010dno i predugo bez lije\u010dni\u010dkog nadzora<\/em> – obja\u0161njava prof. dr. Rustemovi\u0107.<\/p>\n

Kako je jedan od naj\u010de\u0161\u0107e kori\u0161tenih lijekova protiv \u017egaravice i \u017eelu\u010danih ulkusa i Peptoran, bezreceptni lijek koji proizvodi Pliva, kontaktirali smo i zagreba\u010dku farmaceutsku kompaniju.<\/p>\n

Vi\u0161e o ovome mo\u017eete pro\u010ditati na portalu Jutarnji list<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"

Radi se o lijekovima koji se nabavljaju bez recepta i koje na svoju ruku koriste tisu\u0107e ljudi sa \u017eelu\u010danim problemima, prenosi Jutarnji list. Ameri\u010dka agencija za hranu (FDA) i Europska agencija za lijekove (EMA) zatra\u017eile su povla\u010denje s tr\u017ei\u0161ta lijekova protiv \u017egaravice koji sadr\u017ee djelatnu tvar ranitidin proizvo\u0111a\u010da Saraca Laboratories Ltd. Ranitidin sadr\u017ee iznimno popularni […]<\/p>\n","protected":false},"author":9,"featured_media":89841,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[296,1027],"tags":[6112,4333,6111],"class_list":{"0":"post-89840","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-ab","8":"category-hrvatska","9":"tag-karcinogeni","10":"tag-lijekovi","11":"tag-zgaravica"},"yoast_head":"\nZbog sumnje da sadr\u017ee karcinogene povu\u010deni Ranital i Ranix, a Peptoran i drugi se jo\u0161 ispituju - likemetkovic.hr<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/likemetkovic.hr\/zbog-sumnje-da-sadrze-karcinogene-povuceni-ranital-i-ranix-a-peptoran-i-drugi-se-jos-ispituju\/\" \/>\n<meta property=\"og:locale\" content=\"hr_HR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Zbog sumnje da sadr\u017ee karcinogene povu\u010deni Ranital i Ranix, a Peptoran i drugi se jo\u0161 ispituju - likemetkovic.hr\" \/>\n<meta property=\"og:description\" content=\"Radi se o lijekovima koji se nabavljaju bez recepta i koje na svoju ruku koriste tisu\u0107e ljudi sa \u017eelu\u010danim problemima, prenosi Jutarnji list. 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